Recognition of food safety problems brings into focus the importance of primary production. Overuse of antimicrobial drugs in animal breeding is reality it is only a question in what manner and extent it influences on food safety. Use of antimicrobials can cause residues and herby influence safety of meat originating from treated animals. Besides residues, one of the most important and actual side effects is developing of resistance in food borne pathogens. After correct application of antimicrobial drugs tissue residue levels descrease to permitted quantities (below MRL) in prescribed withdrawal period. But even after expiration of withdrawal period residues are still present in edible animal tissues. Residues of enrofloxacine can be detected in meat nine days after the end of treatment, residues in liver are present much longer. Residues were detected in liver until 22. post treatment day. Residues of florfenicole descrease in meat below MRL on third withdrawal day but in liver residues completely expire on seventh post treatment day, while in kidneys they can be still detected. After expiration of withdrawal period residues of florfenicole are still present in edible animal tissues but in permitted quantities. In antimicrobial drug abuse or overuse it is impossible to apply correct withdrawal period this leads to high risk of appearance of dangerous meat on market.
Arhives of Veterinary Medicine is an Open Access Journal.