Infectious stomatitis is a common ailment in captive reptiles, it arises from a combination of predisposing factors such as poor nutritional conditions, habitat issues or stress, where normal oral flora microorganisms act as pathogens, facilitating the disease development. This study aims to describe infectious stomatitis in a captive population of adult Salvator merianae lizards and to propose prophylactic measures for their maintenance in captivity. Within a population of 57 animals, a morbidity rate of 19.2% and a mortality rate of 7% were estimated. Microbiological analysis of oral mucosa revealed Pseudomonas aeruginosa susceptible to ceftazidime, ciprofloxacin, gentamicin, and amikacin. Symptoms ranged from asymptomatic to animals with mild oral cavity lesions or severe stomatitis, with some cases exhibiting respiratory complications. Histopathological examination of lung samples was consistent with caseous pneumonia. Intramuscular ceftazidime treatment and oral disinfection yielded excellent results for lizards with stomatitis, although a favorable response was not observed in animals with pneumonia.
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