Plasmid mediated resistance to quinolones in Salmonella enterica is briefly presented. World wide spread of qnr determinants is evident, indicating the necessity for prudent use of antimicrobials in human and veterinary medicine. In discovering plasmid mediated resistance to quinolones antimicrobial resistance monitoring for β-lactam antibiotics is helpful, since their target genes frequently coexist in plasmid. Nevertheless, 100% reliable method for screening of qnr determinants has not been discovered. The finding of qnr genes and other determinants from the large collection of Salmonella isolates in respective national laboratories, in several countries is described. Individual cases of qnr positive Salmonella from patients, reported in recent years, are also presented.
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